We are enabling the dimensional shift from 2D to 3D tissue histology, developing tissue clearing methods, assays, imaging technology, machine learning-enabled data processing tools and novel methods for big data statistical analysis of spatial anatomy.
Experts in tissue clearing and staining methods
Light sheet imaging on ZEISS Lightsheet Z.1 and Lightsheet 7 microscopes using our Mesoscale imaging System™
Pipeline for computational 3D reconstruction
Machine learning-based image analysis
Use our validated antibodies to measure cFos and Npas4, providing rich, detailed insights into systems-level activity.
The Translucence Neuronal Activity Tissue Clearing Kit is an ideal solution for next-generation 3D histology, making it the go-to option for researchers looking to streamline their processes.
Discount for new users
The Universal Tissue Clearing Kit provides a robust solution for all your tissue clearing needs.
We developed the Mesoscale Imaging System, which makes the ZEISS Lightsheet Z.1 and Lightsheet 7 microscopes compatible with the high refractive index solutions used in iDISCO+ and other tissue clearing methods.
The system’s components exploit the superior optics of the ZEISS Lightsheet Z.1 and Lightsheet 7 microscopes and tune them for cleared tissue.
When Nathan Hyman joined Translucence Biosystems as an undergraduate intern at the University of Michigan, he had no prior laboratory experience. Yet within months, Hyman was generating publication-quality 3D anatomical data that would later be featured at the 2024 Society for Neuroscience meeting. The following article describes how Hyman leveraged iDISCO-based tissue clearing methods, light sheet imaging, and Al-powered whole-brain object segmentation, to generate regionalized data across hundreds of brain regions.
Translucence Biosystems recently participated in the 2024 Society for Neuroscience Meeting, where they had a booth and presented six posters that showcased tools, best practices, and applications of tissue clearing for neuroscience research. Browse the posters and related resources below.
Translucence Biosystems recently presented at the Alzheimer's Association International Conference® (AAIC24) in Philadelphia. Co-Founder & CEO, Damian Wheeler, Ph.D., and expert Chase Redd shared tools, technologies, and 3D histology techniques that are accelerating Alzheimer's research.
Send us your questions and we will get back to you as soon as possible.
info@translucencebio.com
